Unmasking Treatment Resistance: New Strategies to Combat Tumor Evasion in Patients with HER2-Positive Breast Cancer
Despite the initial effectiveness of HER2-targeted therapies, a major clinical challenge remains the development of acquired resistance, where the tumor finds ways to evade the effects of the treatment over time. The mechanisms behind this resistance are complex and multifaceted, often involving alterations to the HER2 receptor itself or the activation of alternative signaling pathways within...
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